

Centrosomes organize the fibers of the mitotic spindle during mitosis that will help pull the sister chromatids apart. To organize the chromsome motion in the cell to help make division efficient as well as ensure all material is present in both daughter cells, the cell has centrosomes at each pole of the cell. In interphase, a nuclear envelope surrounds the nucleus, the DNA is replicated in the S phase, and the sister chromatids join together at the central portion of the chromosome - the centromere. Mitosis is conventionally divided into 5 phases, which include prophase, prometaphase, metaphase, anaphase and telophase and cytokinesis. Mitosis occurs during M phase, which occurs after interphase.

During the S phase, the cell replicates its genome in preparation for cell division or mitosis. During these phases, the cell grows by producing various proteins and cytoplasmic organelles. The largest portion of the cell cycle, interphase, makes up 90% of a cell's life cycle, and is the stage for growing and performing the cellular functions specific to that cell. The interphase is further divided into two G phases- G1 and G2- and an S phase. The mitotic phase is usually the shortest part of any cell cycle.
